Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487182 | 0.77 | MTNR1A (0.39) | MTNR1AMTNR1BSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8485260 | 0.75 | MTNR1A (0.40) | MTNR1AMTNR1BSMN1; SMN2MEN1NPC1 | |
| SCHEMBL8487261 | 0.73 | SLC6A4 (0.36) | MTNR1AMTNR1BMAPTALDH1A1TP53 | |
| SCHEMBL6677201 | 0.73 | MTNR1B (0.65) | MTNR1AMTNR1B | |
| SCHEMBL6677207 | 0.73 | MTNR1B (0.65) | MTNR1AMTNR1B | |
| Methyl Alcohol SCHEMBL27547344 | 0.72 | MTNR1A (0.37) | MTNR1AMTNR1B | |
| SCHEMBL8487259 | 0.72 | MTNR1A (0.36) | MTNR1AMTNR1B | |
| SCHEMBL27463661 | 0.72 | MTNR1A (0.36) | MTNR1AMTNR1B | |
| SCHEMBL6677834 | 0.71 | MTNR1B (0.66) | MTNR1AMTNR1B | |
| SCHEMBL6677838 | 0.71 | MTNR1B (0.66) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |