Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485260 | 0.86 | MTNR1A (0.40) | MTNR1AMTNR1BALOX5MEN1KMT2A | |
| SCHEMBL8489168 | 0.80 | SLC6A4 (0.39) | MTNR1AMTNR1BALOX5 | |
| SCHEMBL8485264 | 0.77 | MTNR1A (0.47) | MTNR1AMTNR1BMEN1KMT2AMAPT | |
| SCHEMBL8487261 | 0.74 | SLC6A4 (0.36) | MTNR1AMTNR1BCYP1A1CYP1A2CYP1B1 | |
| Methyl Alcohol SCHEMBL27547344 | 0.73 | MTNR1A (0.37) | MTNR1AMTNR1BCYP1A1CYP1A2CYP1B1 | |
| Methylamine SCHEMBL27481947 | 0.73 | MTNR1A (0.34) | MTNR1AMTNR1BCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL8487259 | 0.73 | MTNR1A (0.36) | MTNR1AMTNR1BCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL27463661 | 0.73 | MTNR1A (0.36) | MTNR1AMTNR1BCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL6682734 | 0.72 | HTR2C (0.54) | — | |
| SCHEMBL8331072 | 0.72 | HTR2C (0.47) | ALOX5MEN1KMT2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856529-A | ADJUSTMENT OF NERVOUS SYSTEM, ENDOCRINE FUNCTION; REPRODUCTION, BODY WEIGHT AND METABOLISM | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-01-05 | — | — | US | disclosed |