Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFATC1 | O95644 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982299 | 0.84 | ATM (0.41) | NFATC1GSK3BDYRK1AMAPTATM | |
| SCHEMBL8484476 | 0.76 | RPS6KA5 (0.37) | NFATC1GSK3BDYRK1AMAPTPDE2A | |
| SCHEMBL75687 | 0.72 | SLC9A1 (0.43) | MAPTATMHTTNPC1TP53 | |
| SCHEMBL2157981 | 0.68 | CYP11B1 (0.39) | ATMPDE2APDE10A | |
| SCHEMBL7814408 | 0.67 | NPM1 (0.35) | MAPTPDE2APDE10AUSP2HTT | |
| SCHEMBL5982654 | 0.67 | PTPN1 (0.42) | DYRK1AMAPTPDE2APDE10ANPC1 | |
| SCHEMBL822544 | 0.66 | ATM (0.42) | NFATC1GSK3BDYRK1AMAPTATM | |
| SCHEMBL10328043 | 0.65 | SLC9A1 (0.55) | NFATC1GSK3BDYRK1AMAPTATM | |
| SCHEMBL84793 | 0.65 | LTA4H (0.41) | NFATC1GSK3BDYRK1AMAPT | |
| SCHEMBL7811025 | 0.64 | SCN10A (0.35) | MAPTKCNH2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977365-A | HYPOGLYCEMIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |