SCHEMBL75687

SCHEMBL75687

Cn1[c]nc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC9A1 P19634 4/20 0.43
KEAP1 Q14145 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
ATM Q13315 2/20 0.39
POLB P06746 2/20 0.39
MAPK1 P28482 1/20 0.39
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 3/20 0.38
RAB9A P51151 3/20 0.38
MAPT P10636 3/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
PKM P14618 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
GPR3 P46089 1/20 0.36
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
TP53 P04637 1/20 0.35
GLA P06280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16097481 0.74 SLC9A1 (0.36) SLC9A1KEAP1SMN1; SMN2ATMPOLB
SCHEMBL1828029 0.74 SLC9A1 (0.47) SLC9A1SMN1; SMN2POLBMAPK1ALDH1A1
SCHEMBL558259 0.73 ATM (0.39) SLC9A1KEAP1SMN1; SMN2ATMPOLB
SCHEMBL1264258 0.73 MAPT (0.43) SLC9A1KEAP1SMN1; SMN2ATMPOLB
SCHEMBL811367 0.73 ATM (0.39) SLC9A1KEAP1SMN1; SMN2ATMPOLB
SCHEMBL407498 0.73 POLB (0.39) SLC9A1KEAP1SMN1; SMN2ATMPOLB
SCHEMBL655742 0.73 POLB (0.48) SLC9A1KEAP1SMN1; SMN2ATMPOLB
SCHEMBL2073661 0.73 POLB (0.39) SLC9A1KEAP1SMN1; SMN2ATMPOLB
SCHEMBL1381878 0.72 SLC9A1 (0.44) SLC9A1KEAP1SMN1; SMN2ATMPOLB
SCHEMBL2157981 0.72 CYP11B1 (0.39) ATMALDH1A1KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2187 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208902-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2024-06-27 US claimed
WO-2024117767-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2024-06-06 WO claimed
CN-117836296-A Pyrazolopyridone compounds 百济神州有限公司 2024-04-05 CN claimed
US-20240109916-A1 CYTOTOXIC AGENTS PHEON THERAPEUTICS LTD (GB) 2024-04-04 US claimed
CN-117242066-A Novel compound and organic light emitting device comprising the same 株式会社LG化学 2023-12-15 CN claimed
US-11802111-B2 Cyclobutyl amide monoacylglycerol lipase modulators JANSSEN PHARMACEUTICA NV (BE) 2023-10-31 US claimed
US-20230339904-A1 ISOINDOLINONES, PHARMACEUTICAL COMPOSITIONS, AND THERAPEUTIC APPLICATIONS BIOTHERYX, INC. 2023-10-26 US claimed
EP-4217062-A1 CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS JANSSEN Pharmaceutica NV (BE) 2023-08-02 EP claimed
CN-115850274-A Benzophenanthroline compound and application thereof 湖北长江新型显示产业创新中心有限公司 2023-03-28 CN claimed
US-20230084927-A1 GLUCOSE UPTAKE INHIBITORS AND USES THEREOF METABOMED LTD. (IL) 2023-03-16 US claimed
EP-0003560-B1 IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS THE WELLCOME FOUNDATION LIMITED (GB) 1984-05-02 EP claimed
US-4416895-A ANTICOAGULANTS, ANTISHOCK AGENTS BURROUGHS WELLCOME CO. (US) 1983-11-22 US claimed
EP-0061094-A1 Electrophotographic recording material BASF Aktiengesellschaft (DE) 1982-09-29 EP claimed
US-4293462-A Process for the manufacture of enol derivatives, and intermediates CIBA-GEIGY CORPORATION (US) 1981-10-06 US claimed
US-4255328-A CEPHALOSPORINS CIBA-GEIGY CORPORATION (US) 1981-03-10 US claimed
US-4246403-A OPTICAL BRIGHTENERS HOECHST AKTIENGESELLSCHAFT (DE) 1981-01-20 US claimed
EP-0018305-A1 Oxapenem derivatives, their preparation, their use, pharmaceutical compositions containing them, diverse initial compounds and their preparation HOECHST UK LIMITED (GB) 1980-10-29 EP claimed
EP-0003560-A2 Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations THE WELLCOME FOUNDATION LIMITED (GB) 1979-08-22 EP claimed
US-4147864-A Process for the manufacture of 7β-amino-3-cephem-3-ol-4 carboxylic acid compounds CIBA-GEIGY CORPORATION (US) 1979-04-03 US claimed
US-4110533-A PROCESS FOR THE MANUFACTURE OF ENOL DERIVATIVES CIBA-GEIGY CORPORATION (US) 1978-08-29 US claimed