Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA5 | O75582 | 8/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485408 | 0.76 | NFATC1 (0.36) | RPS6KA5DYRK1APDE2ANFATC1GSK3B | |
| SCHEMBL1381878 | 0.76 | SLC9A1 (0.44) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL8484044 | 0.74 | CYP11B1 (0.45) | KDM4EALDH1A1LMNATP53MAPT | |
| SCHEMBL7835972 | 0.70 | ALDH1A1 (0.35) | RPS6KA5KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL5982029 | 0.68 | MAOA (0.37) | KDM4ENPC1ALDH1A1LMNATP53 | |
| SCHEMBL9228815 | 0.68 | USP2 (0.38) | RPS6KA5S1PR1DYRK1AKDM4ENPC1 | |
| SCHEMBL7821616 | 0.68 | TDP1 (0.44) | DYRK1AKDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL11228111 | 0.67 | ACSS2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL7975287 | 0.66 | LTA4H (0.48) | RPS6KA5KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL9911126 | 0.66 | SLC9A1 (0.59) | RPS6KA5KDM5ADYRK1AKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977365-A | HYPOGLYCEMIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |