Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | HTR2C | P28335 | 5/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7092682 | 0.84 | DRD3 (0.54) | DRD3HTR1ASLC6A2SLC6A4HTR2C | |
| SCHEMBL23173231 | 0.77 | SLC6A2 (0.32) | SLC6A2SLC6A4HTR2CSLC6A3 | |
| SCHEMBL9054763 | 0.76 | HTR2C (0.42) | HTR1AHTR2CHTR2ASIGMAR1 | |
| SCHEMBL1009314 | 0.75 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL29349994 | 0.74 | HTR1A (0.56) | DRD3HTR1ADRD2DRD4 | |
| SCHEMBL7597067 | 0.73 | ALDH1A1 (0.49) | HTR1AHTR2CHTR2A | |
| SCHEMBL7597072 | 0.73 | ALDH1A1 (0.49) | HTR1AHTR2CHTR2A | |
| SCHEMBL14968773 | 0.73 | SLC6A4 (0.33) | SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4796823 | 0.73 | HTR2C (0.31) | SLC6A2SLC6A4HTR2C | |
| SCHEMBL2248107 | 0.71 | DRD3 (0.54) | DRD3HTR1AHTR2CHTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968954-A | EXHIBIT SELECTIVE BINDING AFFINITY FOR 5-HYDROXYTRYPTAMINE RECEPTORS | ADIR ET COMPAGNIE (FR) | 1999-10-19 | — | — | US | disclosed |
| EP-0861837-A1 | 2-Aminoindane derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-09-02 | — | — | EP | disclosed |