Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8795501 | 0.89 | KDM4E (0.53) | ALDH1A1GAAKDM4EMAPK1KMT2A | |
| SCHEMBL8483139 | 0.89 | KDM4E (0.56) | ALDH1A1GAAKDM4EMAPK1KMT2A | |
| SCHEMBL1876555 | 0.79 | ALDH1A1 (0.71) | ALDH1A1KDM4EMAPK1KMT2ALMNA | |
| SCHEMBL8488739 | 0.78 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1KMT2ALMNA | |
| SCHEMBL8483983 | 0.78 | CYP2D6 (0.55) | ALDH1A1KDM4EKMT2ALMNAPKM | |
| SCHEMBL8484029 | 0.77 | CYP2D6 (0.54) | ALDH1A1KDM4EKMT2ALMNAPKM | |
| SCHEMBL1880968 | 0.75 | ALDH1A1 (0.72) | ALDH1A1KDM4EMAPK1KMT2ALMNA | |
| SCHEMBL8795385 | 0.73 | POLB (0.61) | ALDH1A1KMT2APKMCYP19A1MAPT | |
| Hydrochloric Acid SCHEMBL8487010 | 0.72 | POLB (0.59) | ALDH1A1KMT2APKMCYP19A1MAPT | |
| SCHEMBL8482951 | 0.71 | RAB9A (0.56) | ALDH1A1KMT2APKMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877196-A | N- 4-(imidazolyl or pyrazolyl)phenyl(oxy, sulfinyl, sulfenyl or sulfonyl)alkyl!carboxamides, sulfonamides or phosphoramides having antiarrhythmic properties | AMERICAN CYANAMID COMPANY (US) | 1999-03-02 | — | — | US | disclosed |