Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.46 |
| ▸ | MAP1LC3A | Q9H492 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494210 | 0.92 | ALOX15 (0.52) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8494200 | 0.92 | ALOX15 (0.52) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL6277209 | 0.91 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8495123 | 0.89 | MAOA (0.54) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8486987 | 0.89 | MAOA (0.54) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL6276971 | 0.88 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8497513 | 0.88 | ALOX15 (0.54) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8497519 | 0.88 | ALOX15 (0.54) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8489475 | 0.87 | KDM4E (0.54) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL8489669 | 0.87 | MAOA (0.52) | ALDH1A1KDM4EHPGDMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981495-A | TREATING HEART DISEASE BY ADMINISTERING TO THE HEART PATIENT A BENOPYRAN DERIVATIVE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-11-09 | — | — | US | disclosed |
| EP-0796854-A1 | Benzopyran derivative and use of said benzopyran derivative for treating heart disease | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-09-24 | — | — | EP | disclosed |