Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16970628 | 0.78 | HCAR2 (0.43) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL96935 | 0.78 | HCAR2 (0.43) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL16970750 | 0.78 | HCAR2 (0.43) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL5519744 | 0.75 | THRB (0.42) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL585330 | 0.75 | TAAR1 (0.41) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL15332155 | 0.73 | CYP3A4 (0.39) | LMNAHIF1AALDH1A1KMT2A | |
| SCHEMBL25039979 | 0.73 | THRB (0.42) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL857 | 0.73 | IDO1 (0.39) | ADRA2ALMNACYP2D6 | |
| SCHEMBL609266 | 0.73 | THRB (0.42) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL6003200 | 0.72 | ADRA2A (0.35) | ADRA2AADRA2CLMNAHIF1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999018082-A1 | NOVEL SUBSTITUTED PYRIDAZINONES | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-15 | — | — | WO | disclosed |