Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3102669 | 0.81 | TAAR1 (0.41) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL2980266 | 0.80 | KMT2A (0.39) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL120227 | 0.80 | KMT2A (0.39) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL7292294 | 0.76 | L3MBTL1 (0.41) | LMNAL3MBTL1KMT2AHTT | |
| SCHEMBL16970750 | 0.75 | HCAR2 (0.43) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL12261012 | 0.75 | THRB (0.40) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL16970628 | 0.75 | HCAR2 (0.43) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL96935 | 0.75 | HCAR2 (0.43) | ADRA2AADRA2CLMNAHIF1AKDM4E | |
| SCHEMBL7644220 | 0.74 | SLC6A4 (0.36) | ADRA2AADRA2CLMNAL3MBTL1KMT2A | |
| SCHEMBL8698025 | 0.74 | LMNA (0.37) | ADRA2AADRA2CLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |