Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 11/20 | 0.74 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.47 |
| ▸ | JAK3 | P52333 | 1/20 | 0.47 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113110 | 0.87 | KDM4E (0.67) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL8442044 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8483738 | 0.84 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL8483933 | 0.83 | PTGS2 (0.78) | PTGS2PTGS1 | |
| SCHEMBL23397418 | 0.82 | ALDH1A1 (0.61) | PTGS2PTGS1KDM4EALDH1A1HPGD | |
| SCHEMBL6725826 | 0.82 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL790509 | 0.79 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL7175144 | 0.77 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL28147345 | 0.77 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL28146262 | 0.77 | PTGS2 (0.69) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932586-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| US-5932586-A | ANTIINFLAMMATORY AGENTS; ANTIPYRETICS | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-08-03 | — | — | US | disclosed |