Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486337 | 1.00 | L3MBTL1 (0.49) | L3MBTL1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL8484165 | 0.99 | L3MBTL1 (0.50) | L3MBTL1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL8484168 | 0.99 | L3MBTL1 (0.50) | L3MBTL1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL8486160 | 0.93 | L3MBTL1 (0.52) | L3MBTL1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL8486156 | 0.93 | L3MBTL1 (0.52) | L3MBTL1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL11704583 | 0.86 | L3MBTL1 (0.47) | L3MBTL1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL12000497 | 0.86 | OPRM1 (0.45) | L3MBTL1OPRM1MAPTSLC6A4MEN1 | |
| SCHEMBL28249200 | 0.85 | KDM4E (0.47) | L3MBTL1OPRM1MAPTOPRD1OPRK1 | |
| SCHEMBL6203970 | 0.83 | RAB9A (0.39) | L3MBTL1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6203975 | 0.83 | RAB9A (0.39) | L3MBTL1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |