Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP10 | P09238 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483699 | 0.84 | MAOB (0.39) | LMNAL3MBTL1MAOBADAM17 | |
| SCHEMBL8486744 | 0.83 | ALDH1A1 (0.36) | LMNAL3MBTL1MEN1ALDH1A1KMT2A | |
| SCHEMBL8486375 | 0.77 | MAOB (0.40) | LMNAMAOBMEN1ALDH1A1RECQL | |
| SCHEMBL8482603 | 0.74 | GRIN1 (0.37) | MAOBMEN1ALDH1A1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL8487938 | 0.74 | — | — | |
| SCHEMBL8485579 | 0.70 | YAP1 (0.40) | LMNAL3MBTL1MAOBMEN1ALDH1A1 | |
| SCHEMBL7209167 | 0.70 | PPARG (0.43) | LMNAL3MBTL1MAOBMMP3MMP10 | |
| SCHEMBL7214886 | 0.70 | PPARG (0.43) | LMNAL3MBTL1MAOBMMP3MMP10 | |
| Hydrochloric Acid SCHEMBL8865801 | 0.70 | SLC6A2 (0.34) | — | |
| SCHEMBL8195162 | 0.68 | MAOB (0.44) | LMNAMAOBMMP3MMP10NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889026-A | 4-hydroxy-piperodine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-03-30 | — | — | US | disclosed |