Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP10 | P09238 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483704 | 0.84 | MAOB (0.41) | MAOB | |
| SCHEMBL8486747 | 0.82 | HTR1A (0.37) | ALDH1A1KMT2AHTR2CSMN1; SMN2KDM4E | |
| SCHEMBL8486371 | 0.77 | LMNA (0.39) | MAOBALDH1A1MEN1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL8486196 | 0.74 | GRIN2D (0.37) | MAOB | |
| SCHEMBL8482605 | 0.74 | LTA4H (0.41) | MAOBALDH1A1MEN1RECQLKMT2A | |
| Hydrochloric Acid SCHEMBL8487939 | 0.73 | GAA (0.35) | LMNA | |
| SCHEMBL8485582 | 0.73 | FFAR1 (0.40) | MAOBALDH1A1MEN1RECQLKMT2A | |
| SCHEMBL7290504 | 0.72 | KDM4E (0.57) | ALDH1A1HTR2BNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8520590 | 0.71 | LMNA (0.38) | ALDH1A1SMN1; SMN2KDM4ELMNASLC6A2 | |
| Hydrochloric Acid SCHEMBL8729781 | 0.70 | LMNA (0.38) | ALDH1A1SMN1; SMN2KDM4ELMNASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889026-A | 4-hydroxy-piperodine derivatives | HOFFMANN-LA ROCHE INC. (US) | 1999-03-30 | — | — | US | disclosed |