Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.57 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486062 | 1.00 | CYP2D6 (0.57) | CYP2D6CYP2C9CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL8487429 | 0.99 | CYP2D6 (0.59) | CYP2D6CYP2C9CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL8485356 | 0.95 | MAPT (0.60) | CYP2D6CYP2C9CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL8616243 | 0.80 | RAB9A (0.69) | MAPTRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8617348 | 0.79 | RAB9A (0.68) | MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8795375 | 0.78 | CYP2D6 (0.49) | CYP2D6CYP2C9CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL8486023 | 0.78 | CYP2D6 (0.49) | CYP2D6CYP2C9CYP3A4CYP1A2CYP2C19 | |
| SCHEMBL11996369 | 0.78 | RAB9A (0.87) | CYP2D6CYP1A2CYP2C19MAPTRAB9A | |
| SCHEMBL8554591 | 0.78 | RAB9A (0.87) | CYP2D6CYP1A2CYP2C19MAPTRAB9A | |
| SCHEMBL1999435 | 0.77 | RAB9A (0.90) | CYP2D6CYP1A2CYP2C19MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877196-A | N- 4-(imidazolyl or pyrazolyl)phenyl(oxy, sulfinyl, sulfenyl or sulfonyl)alkyl!carboxamides, sulfonamides or phosphoramides having antiarrhythmic properties | AMERICAN CYANAMID COMPANY (US) | 1999-03-02 | — | — | US | disclosed |