Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 9/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486023 | 1.00 | CYP2D6 (0.49) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8485356 | 0.80 | MAPT (0.60) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8487429 | 0.79 | CYP2D6 (0.59) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8486062 | 0.78 | CYP2D6 (0.57) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8487176 | 0.78 | CYP2D6 (0.57) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8794811 | 0.76 | CYP2D6 (0.57) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8485506 | 0.76 | CYP2D6 (0.57) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL9711714 | 0.75 | CYP2D6 (0.61) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL8486026 | 0.74 | SMN1; SMN2 (0.40) | CYP2D6CYP3A4CYP2C9CYP1A2CYP2C19 | |
| SCHEMBL27565923 | 0.73 | TBXAS1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792873-A1 | N-(Phenoxyalkyl) carboxamides and their use as antiarrhythmic agents | American Cyanamid Company (US) | 1997-09-03 | — | — | EP | disclosed |