Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486888 | 0.83 | ALDH1A1 (0.65) | ALDH1A1HTTLMNANPSR1SMN1; SMN2 | |
| SCHEMBL1356145 | 0.71 | ADORA2A (0.44) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL11002083 | 0.67 | GLS (0.67) | LMNAKDM4EMAPTATMKMT2A | |
| SCHEMBL1921324 | 0.67 | RECQL (0.65) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL28796085 | 0.66 | MAPT (0.57) | ALDH1A1HTTLMNASMN1; SMN2HPGD | |
| SCHEMBL21840707 | 0.65 | RAB9A (0.76) | ALDH1A1HTTNPSR1SMN1; SMN2KDM4E | |
| SCHEMBL13217032 | 0.65 | MAPT (0.56) | ALDH1A1NPSR1GAAMAPTPKM | |
| SCHEMBL23388323 | 0.65 | ADORA2A (0.67) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL5863497 | 0.65 | TDP1 (0.51) | ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL22157834 | 0.65 | PKM (0.52) | PKMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999018082-A1 | NOVEL SUBSTITUTED PYRIDAZINONES | BASF AKTIENGESELLSCHAFT (DE) | 1999-04-15 | — | — | WO | disclosed |