Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 17/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488133 | 0.78 | GRIN1 (0.39) | MEN1KMT2A | |
| SCHEMBL8488434 | 0.75 | GRIN1 (0.43) | MEN1KMT2A | |
| SCHEMBL8485125 | 0.75 | ALDH1A1 (0.48) | MEN1KMT2A | |
| SCHEMBL8488905 | 0.75 | ALDH1A1 (0.38) | MEN1KMT2A | |
| SCHEMBL8488354 | 0.75 | GRIN1 (0.40) | MEN1KMT2A | |
| SCHEMBL8485738 | 0.72 | SMN1; SMN2 (0.36) | MEN1KMT2A | |
| SCHEMBL8930635 | 0.70 | GRIN1 (0.36) | MEN1KMT2A | |
| SCHEMBL8484920 | 0.69 | GRIN1 (0.59) | — | |
| SCHEMBL8650855 | 0.68 | GRIN1 (0.42) | MEN1KMT2A | |
| SCHEMBL7470510 | 0.66 | RAB9A (0.46) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863917-A | ANXIOLYTIC AGENT, ANTICONVULSANTS, ANALGESICS AND NEUROPROTECTIVES. | PFIZER, INC. (US) | 1999-01-26 | — | — | US | disclosed |
| WO-1997031902-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER RESEARCH AND DEVELOPMENT COMPANY, N.V./S.A. (IE) | 1997-09-04 | — | — | WO | disclosed |
| EP-0792874-A1 | Quinoxaline derivatives useful in therapy | Pfizer Limited (GB) | 1997-09-03 | — | — | EP | disclosed |