Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.34 |
| ▸ | TTPA | P49638 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487392 | 0.88 | HTR1A (0.33) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8485596 | 0.84 | ALOX5 (0.39) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8488308 | 0.83 | ALOX5 (0.38) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8484976 | 0.83 | ALOX5 (0.41) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8485114 | 0.74 | MAPT (0.37) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8484695 | 0.72 | PSEN1 (0.35) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8485088 | 0.72 | ALOX5 (0.31) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL6970017 | 0.70 | MEN1 (0.50) | MAPTMEN1KMT2ATDP1 | |
| SCHEMBL6970021 | 0.70 | MEN1 (0.50) | MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8487812 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |