Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 4/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487549 | 0.88 | ALOX5 (0.40) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8485014 | 0.85 | ALOX5 (0.32) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8484695 | 0.84 | PSEN1 (0.35) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8485088 | 0.84 | ALOX5 (0.31) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8485403 | 0.81 | HTR1A (0.41) | HTR1AADRA1DADRA1AADRA1BALOX5 | |
| SCHEMBL8488335 | 0.77 | ALOX5 (0.32) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL6968237 | 0.75 | MEN1 (0.41) | HTR1AADRA1DADRA1AADRA1BALOX5 | |
| SCHEMBL6980822 | 0.75 | PSEN1 (0.38) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL6971766 | 0.75 | PSEN1 (0.40) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL6966548 | 0.74 | HPGD (0.52) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |