Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | TTPA | P49638 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485596 | 0.93 | ALOX5 (0.39) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8485088 | 0.89 | ALOX5 (0.31) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8484976 | 0.87 | ALOX5 (0.41) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8487549 | 0.83 | ALOX5 (0.40) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8485014 | 0.82 | ALOX5 (0.32) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8485114 | 0.82 | MAPT (0.37) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8484695 | 0.76 | PSEN1 (0.35) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8487812 | 0.74 | — | — | |
| SCHEMBL8487392 | 0.72 | HTR1A (0.33) | ALOX5MAPTMEN1KMT2ATDP1 | |
| SCHEMBL8488335 | 0.72 | ALOX5 (0.32) | ALOX5MAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |