Benzenethiol

Benzenethiol

SCHEMBL8487581

Cc1ccc(S(=O)(O)=S)cc1.Sc1ccccc1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.43
CA9 Q16790 4/20 0.43
CA1 P00915 3/20 0.43
CA2 P00918 3/20 0.43
RECQL P46063 1/20 0.42
HTT P42858 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
GAA P10253 4/20 0.42
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2D6 P10635 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX12 P18054 1/20 0.41
CYP2C19 P33261 1/20 0.41
GFER P55789 1/20 0.41
LMNA P02545 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzenethiol SCHEMBL28329702 0.85 SMN1; SMN2 (0.56) CA12CA9CA1CA2RECQL
SCHEMBL3818649 0.84 GAA (0.56) CA12CA9CA1CA2HTT
SCHEMBL338046 0.84 GAA (0.56) CA12CA9CA1CA2HTT
Chlorobenzene SCHEMBL3023979 0.84 ALDH1A1 (0.47) CA12CA9CA1CA2RECQL
Potassium SCHEMBL367653 0.82 GAA (0.54) CA12CA9CA1CA2HTT
Propane SCHEMBL3021103 0.79 GAA (0.50) CA12CA9CA1CA2SMN1; SMN2
SCHEMBL6603175 0.77 CA2 (0.53) CA12CA9CA1CA2RECQL
Thiocyanic Acid SCHEMBL8512493 0.76 GAA (0.43) CA12CA9CA1CA2SMN1; SMN2
SCHEMBL588340 0.76 SMN1; SMN2 (0.62) CA12CA9CA1CA2SMN1; SMN2
SCHEMBL18817569 0.76 SMN1; SMN2 (0.62) CA12CA9CA1CA2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932731-A HYDROLYZING A HETEROAROMATIC HALOGENATED METHYL SULFIDE IN PRESENCE OF AN ACID SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1999-08-03 US disclosed