Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | CCKBR | P32239 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8632695 | 0.77 | LMNA (0.48) | MC4RLMNASLC6A2FNTAFNTB | |
| SCHEMBL9373817 | 0.74 | KMT2A (0.54) | MC4RLMNAKMT2AMEN1MAPT | |
| SCHEMBL8999053 | 0.74 | CCKBR (0.53) | MC4RCCKBRLMNASMN1; SMN2SLC6A2 | |
| SCHEMBL8999327 | 0.74 | CCKBR (0.51) | MC4RCCKBRLMNASMN1; SMN2SLC6A2 | |
| SCHEMBL27785465 | 0.74 | CCKBR (0.52) | CCKBRLMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8486077 | 0.74 | CCKBR (0.61) | CCKBRLMNAKMT2AMEN1TSHR | |
| SCHEMBL27336638 | 0.73 | KMT2A (0.54) | MC4RKMT2A | |
| SCHEMBL9613706 | 0.73 | CCKBR (0.56) | MC4RCCKBRLMNASMN1; SMN2SLC6A2 | |
| SCHEMBL4121788 | 0.72 | PKM (0.50) | LMNASMN1; SMN2KMT2AMEN1TSHR | |
| SCHEMBL4132288 | 0.72 | PKM (0.50) | LMNASMN1; SMN2KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856354-A | RESPIRATORY SYSTEM DISORDERS, ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL DISORDERS, VISION DEFECTS, ANTIALLERGENS,PAIN, NERVOUS SYSTEM DISORDERS, HEADACHES | WARNER-LAMBERT COMPANY (US) | 1999-01-05 | — | — | US | disclosed |