Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 3/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 3/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486390 | 0.72 | S1PR1 (0.36) | PER2CRY1CRY2 | |
| SCHEMBL8488046 | 0.72 | PER2 (0.42) | PER2CRY1CRY2 | |
| SCHEMBL8489654 | 0.72 | S1PR1 (0.36) | PER2CRY1CRY2 | |
| SCHEMBL8484814 | 0.70 | CRY1 (0.49) | PER2CRY1CRY2 | |
| Tetraxetan SCHEMBL5370171 | 0.63 | HSD17B10 (0.58) | HSD17B10 | |
| SCHEMBL8742068 | 0.63 | MAPT (0.46) | HSD17B10 | |
| SCHEMBL3668924 | 0.63 | MAPT (0.46) | HSD17B10 | |
| SCHEMBL6848102 | 0.63 | HSD17B10 (0.64) | HSD17B10 | |
| SCHEMBL173508 | 0.63 | HSD17B10 (0.64) | HSD17B10 | |
| Tetraxetan SCHEMBL18018 | 0.63 | HSD17B10 (0.64) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919431-A | 1,4,7,10-tetraazacyclododecane derivatives, their use, pharmaceutical agents containing these compounds and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-06 | — | — | US | disclosed |