Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4232792 | 0.68 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL12407928 | 0.68 | NPC1 (0.58) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL9368534 | 0.65 | HPGD (0.38) | ALDH1A1KDM4EHPGDKMT2AMAPT | |
| SCHEMBL5935431 | 0.65 | KMT2A (0.48) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL17446075 | 0.65 | ALDH1A1 (0.65) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL2718551 | 0.63 | LMNA (0.51) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL17446140 | 0.63 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL11125362 | 0.63 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL2982497 | 0.62 | NSD3 (0.42) | ALDH1A1HPGDKMT2AMEN1GAA | |
| SCHEMBL11248969 | 0.62 | L3MBTL1 (0.54) | ALDH1A1KDM4EHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032481-A1 | MUSCARINIC AGENTS AND USE THEREOF TO TREAT GLAUCOMA, MYOPIA AND VARIOUS OTHER CONDITIONS | ALCON LABORATORIES, INC. (US) | 1999-07-01 | — | — | WO | disclosed |