Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 4/20 | 0.50 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | CA1 | P00915 | 6/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15314697 | 0.78 | CA2 (0.52) | CA2CA9CA12PLCG1F2 | |
| SCHEMBL7150046 | 0.76 | LMNA (0.59) | CA2CA9CA12PLCG1F2 | |
| SCHEMBL758697 | 0.76 | CA2 (0.50) | CA2CA9CA12PLCG1F2 | |
| SCHEMBL27338409 | 0.76 | TLR9 (0.67) | CA2CA9CA12F2PRSS1 | |
| SCHEMBL29017279 | 0.76 | CA2 (0.50) | CA2CA9CA12PLCG1F2 | |
| SCHEMBL11273158 | 0.75 | TLR9 (0.58) | CA2CA9CA12CA1MMP2 | |
| SCHEMBL27909407 | 0.74 | ATM (0.41) | CA2CA9CA1MMP2CA5A | |
| SCHEMBL25428935 | 0.73 | TLR9 (0.50) | CA2CA9CA12PLCG1F2 | |
| SCHEMBL19518780 | 0.73 | TLR9 (0.50) | CA2CA9CA12PLCG1F2 | |
| SCHEMBL1460514 | 0.72 | CA2 (0.56) | CA2CA9CA12PLCG1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102970867-A | Aryl and heteroaryl sulfonamides as active agents against abiotic plant stress | BAYER IP GMBH | 2013-03-13 | — | — | CN | claimed |
| CN-102970867-A | Aryl and heteroaryl sulfonamides as active agents against abiotic plant stress | BAYER IP GMBH | 2013-03-13 | — | — | CN | disclosed |
| US-5910482-A | EFFECTIVE TREATING PREGNANCY DISORDER AND PREMATURE LABOR IN A PREGNANT FEMALE MAMMAL | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1999-06-08 | — | — | US | disclosed |