SCHEMBL758697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19518780	0.82	TLR9 (0.50)	CA2PLCG1MMP2CA12CA9
	SCHEMBL25428935	0.82	TLR9 (0.50)	CA2PLCG1MMP2CA12CA9
	SCHEMBL343050	0.78	TLR9 (0.70)	CA2MMP2CA12CA9CA1
	SCHEMBL15314697	0.78	CA2 (0.52)	CA2PLCG1MMP2CA12CA9
	SCHEMBL7150046	0.76	LMNA (0.59)	CA2PLCG1MMP2CA12CA9
	SCHEMBL29017279	0.76	CA2 (0.50)	CA2PLCG1MMP2CA12CA9
	SCHEMBL27649852	0.76	ALDH1A1 (0.54)	CA2MMP2CA12CA9CA1
	SCHEMBL9752512	0.76	TSHR (0.54)	CA2MMP2CA12CA9CA1
	SCHEMBL8488153	0.76	CA2 (0.56)	CA2PLCG1MMP2CA12CA9
	SCHEMBL214852	0.75	TLR9 (0.58)	CA2MMP2CA12CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.