Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485114 | 0.90 | MAPT (0.37) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8485014 | 0.90 | ALOX5 (0.32) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8485088 | 0.83 | ALOX5 (0.31) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8484695 | 0.83 | PSEN1 (0.35) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8485596 | 0.78 | ALOX5 (0.39) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8487392 | 0.77 | HTR1A (0.33) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8484773 | 0.74 | MAPT (0.33) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8488308 | 0.72 | ALOX5 (0.38) | ALOX5MEN1MAPTKMT2ATDP1 | |
| SCHEMBL8485235 | 0.71 | — | — | |
| SCHEMBL8471735 | 0.71 | KCNH2 (0.39) | ALOX5MEN1MAPTKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |