Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15522561 | 0.85 | OPRD1 (0.38) | PLAUPLAUROPRD1SIGMAR1SLC6A4 | |
| SCHEMBL19839947 | 0.85 | OPRD1 (0.38) | PLAUPLAUROPRD1SIGMAR1SLC6A4 | |
| SCHEMBL4559725 | 0.81 | CA2 (0.42) | OPRD1SIGMAR1CHRM5CHRM3CA2 | |
| SCHEMBL9162742 | 0.81 | PLAU (0.36) | PLAUPLAUROPRD1SIGMAR1SLC6A4 | |
| SCHEMBL10413132 | 0.80 | SIGMAR1 (0.43) | PLAUPLAUROPRD1SIGMAR1SLC6A4 | |
| SCHEMBL28706411 | 0.79 | LMNA (0.45) | OPRD1SIGMAR1SLC6A4CHRM5CHRM3 | |
| SCHEMBL28716337 | 0.79 | LMNA (0.45) | OPRD1SIGMAR1SLC6A4CHRM5CHRM3 | |
| SCHEMBL1077282 | 0.79 | SIGMAR1 (0.38) | OPRD1SIGMAR1SLC6A4CHRM5CHRM3 | |
| SCHEMBL2764645 | 0.79 | SIGMAR1 (0.38) | PLAUPLAUROPRD1SIGMAR1SLC6A4 | |
| SCHEMBL1905214 | 0.78 | SIGMAR1 (0.47) | SIGMAR1SLC6A4CA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0907671-A1 | POLYAMIDE COMPOSITIONS FOR REMOVAL OF POLYPHENOLS FROM LIQUIDS | W.R. Grace & Co.-Conn. (US) | 1999-04-14 | — | — | EP | disclosed |
| US-5856429-A | PIPERAZINE CONTAINING POLYAMIDE | W. R. GRACE & CO.-CONN. (US) | 1999-01-05 | — | — | US | disclosed |
| WO-1998000453-A1 | POLYAMIDE COMPOSITIONS FOR REMOVAL OF POLYPHENOLS FROM LIQUIDS | W.R. GRACE & CO.-CONN. (US) | 1998-01-08 | — | — | WO | disclosed |