Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27717556 | 0.98 | MEN1 (0.42) | MEN1KMT2ACYP1A2CYP2C19NPSR1 | |
| SCHEMBL12203852 | 0.87 | OPRM1 (0.46) | MEN1KMT2ASLC6A2GAACDC25A | |
| SCHEMBL18399877 | 0.80 | ALDH1A1 (0.48) | MEN1KMT2ACYP1A2CYP2C19NPSR1 | |
| SCHEMBL8488571 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2ACYP1A2CYP2C19NPSR1 | |
| SCHEMBL31522712 | 0.75 | MAOA (0.47) | MEN1KMT2ANPSR1SLC6A2GAA | |
| SCHEMBL9142803 | 0.75 | MAOA (0.47) | MEN1KMT2ANPSR1SLC6A2GAA | |
| SCHEMBL17206979 | 0.74 | GAA (0.51) | MEN1KMT2ACYP1A2CYP2C19NPSR1 | |
| SCHEMBL29158505 | 0.74 | ALDH1A1 (0.55) | MEN1KMT2ACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL4599210 | 0.74 | ALDH1A1 (0.48) | MEN1KMT2ACYP1A2CYP2C19NPSR1 | |
| SCHEMBL23295125 | 0.73 | LMNA (0.67) | MEN1KMT2ACYP1A2CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999062900-A1 | OXINDOLE DERIVATIVES USED AS NEUROKININ RECEPTOR ANTAGONISTS | SANOFI-SYNTHELABO (FR) | 1999-12-09 | — | — | WO | disclosed |