Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488757 | 0.82 | PER2 (0.30) | — | |
| SCHEMBL8489492 | 0.81 | MAPK1 (0.40) | LMNAALDH1A1SLC6A9POLB | |
| SCHEMBL8488416 | 0.81 | ALDH1A1 (0.39) | LMNAALDH1A1SMN1; SMN2POLBBACE1 | |
| SCHEMBL8489560 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL8489937 | 0.80 | SIGMAR1 (0.33) | SIGMAR1 | |
| SCHEMBL8490617 | 0.78 | S1PR1 (0.36) | SIGMAR1 | |
| SCHEMBL8485655 | 0.78 | S1PR1 (0.36) | SIGMAR1 | |
| SCHEMBL8488572 | 0.76 | BACE1 (0.48) | LMNAALDH1A1BACE1 | |
| SCHEMBL8488562 | 0.73 | ALDH1A1 (0.35) | LMNAALDH1A1CHRM5CHRM1CHRM3 | |
| SCHEMBL8488054 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919431-A | 1,4,7,10-tetraazacyclododecane derivatives, their use, pharmaceutical agents containing these compounds and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-07-06 | — | — | US | disclosed |