Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HK1 | P19367 | 4/20 | 0.33 |
| ▸ | HK2 | P52789 | 4/20 | 0.33 |
| ▸ | PYGB | P11216 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.30 |
| ▸ | GSR | P00390 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fotemustine SCHEMBL5508629 | 0.95 | LMNA (0.57) | LMNAKDM4ECYP2D6CYP2C19MAPK1 | |
| Chlorozotocin SCHEMBL6014822 | 0.84 | LMNA (0.54) | LMNAKDM4ECYP2D6CYP2C19BLM | |
| Chlorozotocin SCHEMBL11409484 | 0.83 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19MAPK1 | |
| Chlorozotocin SCHEMBL11409480 | 0.83 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19MAPK1 | |
| Chlorozotocin SCHEMBL8539 | 0.83 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19MAPK1 | |
| Chlorozotocin SCHEMBL1648834 | 0.83 | LMNA (0.64) | LMNAKDM4ECYP2D6CYP2C19MAPK1 | |
| Chlorozotocin SCHEMBL6051206 | 0.82 | LMNA (0.51) | LMNAKDM4ECYP2D6CYP2C19BLM | |
| Chlorozotocin SCHEMBL19520816 | 0.82 | LMNA (0.63) | LMNAKDM4ECYP2D6CYP2C19MAPK1 | |
| Fotemustine SCHEMBL16174560 | 0.81 | ALDH1A1 (0.44) | LMNACYP2C19ALDH1A1ADRA2ASMN1; SMN2 | |
| Fotemustine SCHEMBL8880 | 0.81 | ALDH1A1 (0.44) | LMNACYP2C19ALDH1A1ADRA2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999065875-A1 | TELOMERASE INHIBITORS | GERON CORPORATION (US) | 1999-12-23 | — | — | WO | disclosed |