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Sugi Predict / Compounds / Chlorozotocin

Chlorozotocin

Chlorozotocin

SCHEMBL6051206

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nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 2/20 0.51
▸ NFKB1 P19838 1/20 0.51
▸ BLM P54132 1/20 0.51
▸ PMP22 Q01453 1/20 0.51
▸ KDM4E B2RXH2 1/20 0.41
▸ CYP2D6 P10635 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorozotocin SCHEMBL6014822 0.97 LMNA (0.54) LMNANFKB1BLMPMP22KDM4E
Chlorozotocin SCHEMBL5512910 0.86 LMNA (0.68) LMNANFKB1BLMPMP22KDM4E
Fotemustine SCHEMBL5508629 0.85 LMNA (0.57) LMNAKDM4ECYP2D6CYP2C19
Chlorozotocin SCHEMBL8489015 0.82 LMNA (0.48) LMNABLMPMP22KDM4ECYP2D6
Nimustine SCHEMBL6912494 0.73 BLM (0.67) LMNANFKB1BLMPMP22
Chlorozotocin SCHEMBL10424026 0.73 LMNA (0.78) LMNABLMPMP22KDM4ECYP2D6
Nimustine SCHEMBL8414 0.71 BLM (1.00) LMNANFKB1BLMPMP22
Ranimustine SCHEMBL3024489 0.71 BLM (0.68) LMNANFKB1BLMPMP22
Streptozosin SCHEMBL22408645 0.71 LMNA (0.70) LMNANFKB1BLMPMP22KDM4E
Nimustine SCHEMBL98303 0.70 BLM (0.98) LMNANFKB1BLMPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1687041-A2 SOFT TISSUE IMPLANTS AND ANTI-SCARRING AGENTS Angiotech International AG (CH) 2006-08-09 — — EP disclosed
WO-2005051316-A2 POLYMER COMPOSITIONS AND METHODS FOR THEIR USE ANGIOTECH INTERNATIONAL AG (CH) 2005-06-09 — — WO disclosed
WO-2005051483-A2 ELECTRICAL DEVICES AND ANTI-SCARRING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-06-09 — — WO disclosed
WO-2005051444-A2 SOFT TISSUE IMPLANTS AND ANTI-SCARRING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-06-09 — — WO disclosed