Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488451 | 0.90 | HTR1A (0.49) | ALDH1A1KDM4EHTR1AHTR1DHTR1B | |
| SCHEMBL28813326 | 0.81 | DRD3 (0.65) | ALDH1A1SMN1; SMN2DRD2DRD3DRD4 | |
| SCHEMBL7371157 | 0.81 | DRD4 (0.58) | ALDH1A1SMN1; SMN2DRD2DRD3DRD4 | |
| SCHEMBL27976215 | 0.76 | HRH3 (0.73) | ALDH1A1DRD2DRD3DRD4MEN1 | |
| SCHEMBL8489470 | 0.76 | KDM4E (0.60) | ALDH1A1KDM4ESMN1; SMN2HTR1AHTR1D | |
| SCHEMBL1307575 | 0.76 | TSHR (0.53) | KDM4ESMN1; SMN2LMNAMAPK1LTA4H | |
| SCHEMBL27975888 | 0.73 | KCNA5 (0.65) | ALDH1A1DRD2DRD3DRD4MEN1 | |
| SCHEMBL8489392 | 0.73 | SMN1; SMN2 (0.56) | ALDH1A1KDM4ESMN1; SMN2DRD2DRD3 | |
| SCHEMBL14970728 | 0.71 | LTA4H (0.53) | ALDH1A1KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL27976210 | 0.71 | TDP1 (0.65) | ALDH1A1KDM4EHTR1AHTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |