Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489397 | 0.90 | ALDH1A1 (0.50) | HTR1AHTR1DHTR1BABCB1MEN1 | |
| SCHEMBL7370004 | 0.81 | DRD2 (0.50) | KMT2AKDM4EALDH1A1MAPK1DRD2 | |
| SCHEMBL8489470 | 0.75 | KDM4E (0.60) | HTR1AHTR1DHTR1BABCB1MEN1 | |
| SCHEMBL8488449 | 0.74 | SIGMAR1 (0.51) | HTR1AHTR1DHTR1BMEN1KMT2A | |
| SCHEMBL13020890 | 0.73 | MAPK1 (0.55) | KDM4EMAPTMAPK1 | |
| SCHEMBL5060367 | 0.72 | HRH3 (0.64) | HTR1AMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2157291 | 0.71 | SIGMAR1 (0.69) | ALDH1A1DRD3HRH3 | |
| SCHEMBL7371157 | 0.70 | DRD4 (0.58) | ALDH1A1MAPK1DRD2DRD4DRD3 | |
| SCHEMBL14970728 | 0.70 | LTA4H (0.53) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL23775600 | 0.70 | SIGMAR1 (0.68) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |