Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | PTPRG | P23470 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 1/20 | 0.38 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491129 | 0.93 | OPRM1 (0.39) | SIGMAR1FDPSSMN1; SMN2MEN1LMNA | |
| SCHEMBL8490323 | 0.91 | SIGMAR1 (0.40) | SIGMAR1FDPSSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL7616402 | 0.81 | MAPT (0.41) | SMN1; SMN2KMT2A | |
| SCHEMBL3257459 | 0.78 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP2D6KMT2AKDM4A | |
| SCHEMBL10522339 | 0.76 | PTPN1 (0.43) | SMN1; SMN2LMNAOPRM1PTPRCPTPN2 | |
| SCHEMBL5418047 | 0.75 | FKBP1A (0.46) | KDM4EMEN1KMT2A | |
| SCHEMBL7615614 | 0.75 | SMN1; SMN2 (0.42) | FDPSSMN1; SMN2CYP2D6KMT2AKDM4A | |
| SCHEMBL10522480 | 0.75 | KMT2A (0.42) | SIGMAR1KDM4EKMT2AL3MBTL1 | |
| SCHEMBL7617574 | 0.73 | NPSR1 (0.41) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5428513 | 0.71 | MAPT (0.39) | FDPSSMN1; SMN2KDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999058490-A2 | NOVEL ARYL-HYDRO NAPHTHALENAL KANAMINES | AKZO NOBEL N.V. (NL) | 1999-11-18 | — | — | WO | disclosed |