Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 6/20 | 0.57 |
| ▸ | CA2 | P00918 | 6/20 | 0.57 |
| ▸ | CA9 | Q16790 | 4/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1093723 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL16479320 | 0.82 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL8014556 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL25062005 | 0.81 | LMNA (0.58) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL394046 | 0.80 | LMNA (0.55) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL16473945 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL8489881 | 0.78 | CA1 (0.56) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL8123878 | 0.78 | CA1 (0.60) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL42974 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1CA1CA2 | |
| SCHEMBL446811 | 0.77 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999005141-A1 | HISTAMINE H3 RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-02-04 | — | — | WO | disclosed |