Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053601 | 0.84 | LMNA (0.55) | LMNAALDH1A1MAPK1L3MBTL1CA1 | |
| SCHEMBL18673 | 0.83 | ALDH1A1 (0.68) | LMNAALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL3963428 | 0.83 | ALDH1A1 (0.68) | LMNAALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL30200673 | 0.82 | CA1 (0.50) | LMNAALDH1A1MAPK1L3MBTL1CA1 | |
| SCHEMBL26696191 | 0.82 | CA2 (0.56) | LMNAALDH1A1MAPK1L3MBTL1CA1 | |
| SCHEMBL31626600 | 0.81 | LMNA (0.52) | LMNAALDH1A1MAPK1L3MBTL1CA1 | |
| SCHEMBL118235 | 0.81 | ALDH1A1 (0.66) | LMNAALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL28600680 | 0.81 | ALDH1A1 (0.66) | LMNAALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL2926392 | 0.81 | ALDH1A1 (0.66) | LMNAALDH1A1MAPK1L3MBTL1TDP1 | |
| SCHEMBL20624816 | 0.81 | ALDH1A1 (0.66) | LMNAALDH1A1MAPK1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4090658-A1 | THERAPEUTIC AGENTS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2022-11-23 | — | — | EP | disclosed |
| CN-115038697-A | Therapeutic agents and methods of treatment | 佛罗里达大学研究基金公司 | 2022-09-09 | — | — | CN | disclosed |
| WO-2021146536-A1 | THERAPEUTIC AGENTS AND METHODS OF TREATMENT | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2021-07-22 | — | — | WO | disclosed |
| EP-2374802-B1 | KYNURENINE PRODUCTION INHIBITOR | KYOWA HAKKO KIRIN CO LTD (JP) | 2014-04-23 | — | — | EP | disclosed |
| US-8673908-B2 | Kynurenine production inhibitor | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-03-18 | — | — | US | disclosed |
| CN-103224506-A | Antiviral indoles | ANGELETTI P IST RICHERCHE BIO | 2013-07-31 | — | — | CN | disclosed |
| EP-2121707-B1 | ANTIVIRAL INDOLES | ANGELETTI P IST RICHERCHE BIO (IT) | 2012-12-05 | — | — | EP | disclosed |
| US-8101595-B2 | Antiviral indoles | Istituto di Ricerche di Biologia Molecolare P. Angletti SpA (IT) | 2012-01-24 | — | — | US | disclosed |
| EP-2374802-A1 | KYNURENINE PRODUCTION INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYOWA KIRIN CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| US-7767660-B2 | Antiviral indoles | ISTITUTO DI RICHERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-08-03 | — | — | US | disclosed |
| US-20100076046-A1 | Antiviral Indoles | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-03-25 | — | — | US | disclosed |
| EP-2121707-A1 | ANTIVIRAL INDOLES | Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. (IT) | 2009-11-25 | — | — | EP | disclosed |
| CN-101563352-A | Antiviral indoles | ANGELETTI P IST RICHERCHE BIO (IT) | 2009-10-21 | — | — | CN | disclosed |
| US-20080214522-A1 | Antiviral indoles | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-09-04 | — | — | US | disclosed |
| WO-2008075103-A1 | ANTIVIRAL INDOLES | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076046-A1 | Antiviral Indoles | IDO1, ZC3HAV1, IFNAR1 | LMNA 1700/4885ALDH1A1 1086/4885MAPK1 4419/4885 |
| US-20080214522-A1 | Antiviral indoles | IDO1, ZC3HAV1, YBX1 | LMNA 1814/4885ALDH1A1 1120/4885MAPK1 4472/4885 |
| US-20110237584-A1 | KYNURENINE PRODUCTION INHIBITOR | KYNU, KMO, IDO1 | LMNA 4183/4885ALDH1A1 1689/4885MAPK1 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.