SCHEMBL25062005

SCHEMBL25062005

O=C(CS(=O)(=O)c1ccccc1)OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
ALDH1A1 P00352 3/20 0.58
MAPK1 P28482 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
KMT2A Q03164 3/20 0.53
HSD11B1 P28845 4/20 0.50
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
MAPT P10636 1/20 0.48
CDC25B P30305 1/20 0.48
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
GAA P10253 1/20 0.47
MMP2 P08253 1/20 0.46
MMP7 P09237 1/20 0.46
MMP14 P50281 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24390159 0.85 KMT2A (0.47) LMNAALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL20534388 0.85 GLA (0.50) LMNAALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL25062003 0.83 TDP1 (0.54) ALDH1A1MAPK1L3MBTL1KMT2AHSD11B1
SCHEMBL8014556 0.83 ALDH1A1 (0.58) LMNAALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL24390160 0.82 KMT2A (0.44) LMNAALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL20283988 0.81 HSD11B1 (0.46) LMNAALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL28297415 0.81 KMT2A (0.48) LMNAALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL8489884 0.81 ALDH1A1 (0.59) LMNAALDH1A1MAPK1L3MBTL1KMT2A
SCHEMBL2024141 0.81 KMT2A (0.73) ALDH1A1MAPK1KMT2AHSD11B1MAPT
SCHEMBL16479320 0.81 ALDH1A1 (0.59) LMNAALDH1A1MAPK1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230054928-A1 METHOD FOR PREPARING CARBONYL SULFONE SOOCHOW UNIVERSITY (CN) 2023-02-23 US disclosed
CN-1163480-C Styryl sulfone anticancer agents ̹�ն���ѧ 2004-08-25 CN disclosed
CN-1273580-A Styryl sulfone anticancer agents UNIV TEMPLE (US) 2000-11-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230054928-A1 METHOD FOR PREPARING CARBONYL SULFONE TST, CBS, STS LMNA 2866/4885ALDH1A1 297/4885MAPK1 1830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.