Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GYS1 | P13807 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491346 | 0.81 | ABCC8 (0.61) | APOBEC3GNOTUMABCC8KCNJ11XDH | |
| SCHEMBL8493733 | 0.81 | APOBEC3G (0.40) | APOBEC3GMAPTLMNANOTUMABCC8 | |
| SCHEMBL4898151 | 0.76 | KDM4E (0.51) | MAPTLMNAALDH1A1GAADYRK1A | |
| SCHEMBL14280350 | 0.76 | CCNE1 (0.70) | CCNE2CCNE1CDK2MAPTALDH1A1 | |
| SCHEMBL19459337 | 0.75 | KIF11 (0.42) | NOTUMALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL19926357 | 0.74 | MAPT (0.55) | CCNE2CCNE1CDK2MAPTLMNA | |
| SCHEMBL4009647 | 0.72 | MAPK1 (0.47) | MAPTLMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL22126016 | 0.72 | IKBKB (0.59) | CCNE2CCNE1CDK2APOBEC3GMAPT | |
| SCHEMBL6572637 | 0.71 | HPGDS (0.41) | MAPTPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL8495521 | 0.69 | ABCC8 (0.50) | MAPTNOTUMABCC8KCNJ11XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999062885-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)PYRAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |