Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | GYS1 | P13807 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8493563 | 0.88 | ABCC8 (0.47) | APOBEC3GMAPTRAB9ANOTUMABCC8 | |
| SCHEMBL8490498 | 0.81 | CCNE2 (0.44) | APOBEC3GMAPTRAB9ANOTUMABCC8 | |
| SCHEMBL8495434 | 0.79 | ACHE (0.35) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL8491346 | 0.78 | ABCC8 (0.61) | APOBEC3GNOTUMABCC8KCNJ11XDH | |
| SCHEMBL5528929 | 0.67 | MAPT (0.70) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL2660487 | 0.67 | NPBWR1 (0.54) | MAPTRAB9AMEN1KMT2ALMNA | |
| SCHEMBL8495521 | 0.67 | ABCC8 (0.50) | MAPTRAB9ANOTUMABCC8KCNJ11 | |
| SCHEMBL7529478 | 0.66 | KDM4E (0.57) | APOBEC3GMAPTRAB9ANOTUMXDH | |
| SCHEMBL8493201 | 0.66 | TDP1 (0.50) | APOBEC3GMAPTRAB9ANOTUMABCC8 | |
| SCHEMBL28198 | 0.66 | CA1 (0.67) | MAPTLMNATDP1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999062885-A1 | SUBSTITUTED 1-(4-AMINOPHENYL)PYRAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |