Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525706 | 0.89 | LMNA (0.37) | LMNAPOLBMLYCDPTGDR2HCRTR1 | |
| SCHEMBL8524250 | 0.87 | LMNA (0.37) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL8524334 | 0.85 | HCRTR2 (0.43) | MLYCDPTGDR2HCRTR1HCRTR2 | |
| SCHEMBL8817056 | 0.84 | MLYCD (0.41) | LMNAPOLBALDH1A1MLYCDPTGDR2 | |
| SCHEMBL8488086 | 0.83 | MLYCD (0.40) | LMNAPOLBKDM4EALDH1A1MLYCD | |
| SCHEMBL8494706 | 0.83 | KDM4E (0.39) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL8492222 | 0.82 | ALDH1A1 (0.42) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL8490972 | 0.82 | KDM4E (0.38) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL7613973 | 0.81 | MLYCD (0.41) | LMNAPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL8494698 | 0.80 | LMNA (0.35) | LMNAPOLBGAAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |