Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492757 | 0.88 | FTO (0.39) | RAB9AL3MBTL1SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8488994 | 0.88 | MAPT (0.40) | RAB9ASMN1; SMN2NPSR1ALDH1A1MAPT | |
| SCHEMBL8488359 | 0.84 | ALDH1A1 (0.37) | NPSR1ALDH1A1MAPTTDP1KDM4E | |
| SCHEMBL8496033 | 0.81 | KDM4E (0.35) | ALDH1A1KDM4E | |
| SCHEMBL8488228 | 0.81 | KDM4E (0.35) | RAB9ASMN1; SMN2NPSR1ALDH1A1KDM4E | |
| SCHEMBL8493394 | 0.81 | NR1H4 (0.36) | RAB9ASMN1; SMN2NPSR1ALDH1A1KDM4E | |
| SCHEMBL8492065 | 0.79 | THRB (0.40) | L3MBTL1ALDH1A1MAPTMAPK1KDM4E | |
| SCHEMBL8492238 | 0.79 | HPGD (0.33) | SMN1; SMN2NPSR1ALDH1A1KDM4E | |
| SCHEMBL8492682 | 0.78 | SMURF2 (0.40) | RAB9ASMN1; SMN2NPSR1ALDH1A1KDM4E | |
| SCHEMBL8491936 | 0.77 | NR1H4 (0.33) | RAB9ASMN1; SMN2ALDH1A1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |