Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 4/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974082 | 0.72 | HTR6 (0.46) | HTR6METMAPTAKR1B1 | |
| SCHEMBL27825213 | 0.70 | L3MBTL1 (0.47) | HTR6METMAPTL3MBTL1 | |
| SCHEMBL28746965 | 0.70 | HTR6 (0.41) | HTR6METSLC6A2MAPTL3MBTL1 | |
| (Phenylsulfonyl)Benzene SCHEMBL7774155 | 0.66 | HTR6 (0.82) | HTR6MAPTL3MBTL1HSD11B1 | |
| SCHEMBL4728735 | 0.63 | HTR6 (0.48) | HTR6NAMPTMETAKR1B1 | |
| (Phenylsulfonyl)Benzene SCHEMBL9617906 | 0.62 | HTR6 (0.58) | HTR6L3MBTL1HSD11B1 | |
| (Phenylsulfonyl)Benzene SCHEMBL28237512 | 0.61 | HTR6 (0.93) | HTR6MAPTL3MBTL1HSD11B1 | |
| (Phenylsulfonyl)Benzene SCHEMBL9642349 | 0.60 | HTR6 (0.78) | HTR6MAPTL3MBTL1HSD11B1 | |
| SCHEMBL11570944 | 0.60 | ABCB1 (0.43) | HTR6METAKR1B1 | |
| SCHEMBL14131967 | 0.60 | HTR6 (0.54) | HTR6L3MBTL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999006377-A1 | DERIVATIVES OF 1-((3,3-DIMETHYL-3-SILABUTOXY)METHYL)-2-(PHENYLSULFONYL)IMIDAZOLE | GLIATECH, INC. (US) | 1999-02-11 | — | — | WO | disclosed |