Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 14/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496147 | 0.77 | GCGR (0.47) | LTB4RLTB4R2 | |
| SCHEMBL27463361 | 0.77 | PTGER1 (0.44) | LTB4RLTB4R2MCL1ERN1MGAM | |
| SCHEMBL27300408 | 0.75 | LTB4R (0.54) | LTB4RLTB4R2MCL1 | |
| SCHEMBL4382835 | 0.71 | CYP4F2 (0.43) | MGAMGAASIMGAM2 | |
| SCHEMBL3201478 | 0.69 | CNR1 (0.50) | BCHE | |
| SCHEMBL26823115 | 0.69 | C5AR1 (0.49) | MCL1BCHE | |
| SCHEMBL13076466 | 0.68 | BRD4 (0.56) | MCL1 | |
| SCHEMBL2954865 | 0.68 | KDM4E (0.48) | ERN1GAA | |
| SCHEMBL16797594 | 0.68 | HTR1A (0.53) | GAABCHE | |
| SCHEMBL16056330 | 0.68 | MRGPRX4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5914340-A | ADMINISTERING TO TREAT OR INHIBIT SKIN DISORDERS SUCH AS ATOPIC DERMATITIS, CONTACT DERMATITIS, BULLOUS PEMPHIGOID, URTICARIA DISEASES, PETYRIASIS RUBRA PILARIS AND DYSHEDROSIS | ELI LILLY AND COMPANY (US) | 1999-06-22 | — | — | US | disclosed |
| US-5910505-A | Leukotriene antagonists for use in the treatment or inhibition of oral squamous cell carcinoma | ELI LILLY AND COMPANY (US) | 1999-06-08 | — | — | US | disclosed |
| US-5817684-A | ADMINISTERING AN AROMATIC ALCOHOL COMPOUND | ELI LILLY AND COMPANY (US) | 1998-10-06 | — | — | US | disclosed |