Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569951 | 0.81 | PTGER1 (0.39) | PTGER1MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL27300408 | 0.80 | LTB4R (0.54) | PTGER1MCL1LTB4RLTB4R2 | |
| SCHEMBL8492678 | 0.77 | LTB4R (0.45) | MCL1MGAMGAASIMGAM2 | |
| SCHEMBL2954865 | 0.75 | KDM4E (0.48) | PTGER1MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL13076466 | 0.75 | BRD4 (0.56) | PTGER1MAPTLMNAL3MBTL1MCL1 | |
| SCHEMBL16056330 | 0.75 | MRGPRX4 (0.50) | PTGER1LMNASSTR5 | |
| SCHEMBL27090052 | 0.75 | L3MBTL1 (0.51) | PTGER1MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL290026 | 0.74 | PTGER1 (0.52) | PTGER1MAPTLMNAL3MBTL1MCL1 | |
| SCHEMBL1894477 | 0.73 | ELANE (0.58) | PTGER1MAPTLMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8283688 | 0.73 | ALDH1A1 (0.67) | MAPTLMNAL3MBTL1ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142768-A | Use of PLA2 inhibitors as treatment for Alzheimer's disease | LILLY CO ELI (US) | 1997-02-12 | — | — | CN | disclosed |