Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2310548 | 0.82 | CYP1A2 (0.36) | TSHRMAOAMAOBSMN1; SMN2 | |
| SCHEMBL11863652 | 0.74 | LTA4H (0.41) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL13502568 | 0.73 | HTR1A (0.36) | LTA4HTSHRUTS2R | |
| SCHEMBL11129306 | 0.73 | MMP2 (0.38) | LTA4HTSHRMMP2MMP3MMP9 | |
| SCHEMBL10363964 | 0.71 | LTA4H (0.38) | LTA4HTSHRMAOANR1H2BAX | |
| Diphenylether SCHEMBL4639231 | 0.70 | LTA4H (0.71) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL3893562 | 0.69 | LTA4H (0.92) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL22129853 | 0.69 | LTA4H (0.92) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL122719 | 0.69 | LTA4H (0.92) | LTA4HTSHRMAOANR1H2BAX | |
| Diphenylether SCHEMBL27459589 | 0.69 | LTA4H (0.92) | LTA4HTSHRMAOANR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999038833-A1 | PROCESS FOR THE HALOGENATION OF ALDEHYDES AND KETONES | BROMINE COMPOUNDS LTD. (IL) | 1999-08-05 | — | — | WO | disclosed |