SCHEMBL849381

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11797035	0.85	TRPA1 (0.43)	BACE1CA2GABRA1GABRB2MAPT
	SCHEMBL27720252	0.83	CA1 (0.38)	CSNK2A1CSNK2A2CSNK2BCSNK2A3BACE1
	SCHEMBL3483919	0.81	GABRA1 (0.38)	BACE1CA2GABRA1GABRB2MAPT
	SCHEMBL1696358	0.80	CSNK2A1 (0.49)	CSNK2A1CSNK2A2CSNK2BCSNK2A3BACE1
	SCHEMBL11809085	0.79	GABRA1 (0.37)	CSNK2A1CSNK2A2CSNK2BCSNK2A3BACE1
	SCHEMBL27778402	0.79	ABAT (0.38)	CSNK2A1CA2CA1CA12CA4
	SCHEMBL3484733	0.79	BACE1 (0.39)	BACE1CA2CA1CA12CA4
	SCHEMBL14864128	0.78	CSNK2A1 (0.47)	CSNK2A1CSNK2A2CSNK2BCSNK2A3BACE1
	SCHEMBL13443568	0.78	CSNK2A1 (0.47)	CSNK2A1CSNK2A2CSNK2BCSNK2A3BACE1
	SCHEMBL2037286	0.77	CSNK2A1 (0.46)	CSNK2A1CSNK2A2CSNK2BCSNK2A3BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.