Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8494706 | 0.90 | KDM4E (0.39) | LMNAGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8524833 | 0.89 | KDM4E (0.34) | LMNAKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL8491726 | 0.87 | L3MBTL1 (0.35) | LMNAKDM4EHSD17B10USP2MEN1 | |
| SCHEMBL8525760 | 0.87 | LMNA (0.33) | LMNAKDM4EHSD17B10USP2MEN1 | |
| SCHEMBL8524553 | 0.85 | HCRTR2 (0.40) | LMNAKDM4EHSD17B10USP2MEN1 | |
| SCHEMBL8492214 | 0.82 | KDM4E (0.37) | LMNAGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8524884 | 0.80 | LMNA (0.34) | LMNAKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL8490765 | 0.80 | L3MBTL1 (0.35) | LMNAKDM4EHSD17B10ALDH1A1USP2 | |
| SCHEMBL8492222 | 0.80 | ALDH1A1 (0.42) | LMNAGAAKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL8525868 | 0.80 | LMNA (0.37) | LMNAGAAKDM4EHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999003856-A1 | 4-BENZOYL-ISOXAZOLE- AND -PYRAZOLE DERIVATIVES AND 2-CYANO 1,3-DIONE DERIVATIVES AS HERBICIDES | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-28 | — | — | WO | disclosed |