Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL746794 | 0.66 | LMNA (0.64) | CNR2MAPK14LMNAGAAPTGS1 | |
| SCHEMBL8488832 | 0.64 | DHODH (0.46) | CNR2CYP2C19CYP2C9HTR2BMAPK14 | |
| SCHEMBL28815055 | 0.64 | LMNA (0.62) | CNR2MAPK14LMNAGAAPTGS1 | |
| SCHEMBL8891026 | 0.64 | SMN1; SMN2 (0.48) | CNR2LMNACTNNB1WNT3A | |
| SCHEMBL30681561 | 0.61 | LMNA (0.62) | LMNAGAAP2RX7DPP4DPP7 | |
| SCHEMBL4332285 | 0.61 | LMNA (0.49) | CNR2CYP2C19CYP2C9LMNAGAA | |
| SCHEMBL7085218 | 0.61 | CTNNB1 (0.51) | CNR2LMNAGAARORCPTGS1 | |
| SCHEMBL1819622 | 0.61 | LMNA (0.62) | LMNAGAAP2RX7DPP4DPP7 | |
| SCHEMBL8329113 | 0.60 | RBP4 (0.44) | CNR2CYP2C19CYP2C9HTR2BMAPK14 | |
| SCHEMBL3717986 | 0.60 | GAA (0.56) | CNR2LMNAGAACTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |